特立氟胺 Teriflunomide
交易须知
teriflunomide产品活性：teriflunomide是来氟米特的活性代谢产物，是用于治疗类风湿性关节炎的药物。 它抑制嘧啶合成，因此有效降低t细胞和b细胞增殖。
研究领域：others
作用靶点：others
in vitro: teriflunomide primarily acts as an inhibitor of dihydroorotate dehydrogenase (dhodh), a key mitochondrial enzyme involved in the de novo synthesis of pyrimidines in rapidly proliferating cells. by reducing the activity of high-avidity proliferating t lymphocytes and b lymphocytes, teriflunomide likely attenuates the inflammatory response to autoantigens in ms. thus, teriflunomide can be considered a cytostatic rather than a cytotoxic drug to leukocytes.
in vivo: teriflunomide has demonstrated beneficial effects in two independent animal models of demyelinating disease. in the dark agouti rat model of experimental autoimmune encephalitis (eae), teriflunomide administration results in clinical, histopathological, and electrophysiological evidence of efficacy both as a prophylactic and therapeutic agent. similarly, in the female lewis rat model of eae, teriflunomide administration results in beneficial prophylactic and therapeutic clinical effects, with a delay in disease onset and symptom severity.
相关产品：fda-approved drug library plus | drug repurposing compound library | fda-approved drug library mini | covalent screening library | fda-approved drug library | drug repurposing compound library plus | bioactive compound library plus | sbe-β-cd | cyclosporin a | h2dcfda | gw4869 | mptp hydrochloride | etomoxir | mitoquinone mesylate | bapta-am | gsk2795039 | jc-1 | monocrotaline | auranofin | d-luciferin | dapi dihydrochloride | dtt | cfse | solutol hs-15 | auxinole | bptes | ademetionine | nile red | nadph tetrasodium salt | mtt | isa-2011b | l-ascorbic acid | 3x flag peptide | propidium iodide | wnk463 | tocofersolan
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特立氟胺 Teriflunomide
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teriflunomide产品活性：teriflunomide是来氟米特的活性代谢产物，是用于治疗类风湿性关节炎的药物。 它抑制嘧啶合成，因此有效降低t细胞和b细胞增殖。
研究领域：others
作用靶点：others
in vitro: teriflunomide primarily acts as an inhibitor of dihydroorotate dehydrogenase (dhodh), a key mitochondrial enzyme involved in the de novo synthesis of pyrimidines in rapidly proliferating cells. by reducing the activity of high-avidity proliferating t lymphocytes and b lymphocytes, teriflunomide likely attenuates the inflammatory response to autoantigens in ms. thus, teriflunomide can be considered a cytostatic rather than a cytotoxic drug to leukocytes.
in vivo: teriflunomide has demonstrated beneficial effects in two independent animal models of demyelinating disease. in the dark agouti rat model of experimental autoimmune encephalitis (eae), teriflunomide administration results in clinical, histopathological, and electrophysiological evidence of efficacy both as a prophylactic and therapeutic agent. similarly, in the female lewis rat model of eae, teriflunomide administration results in beneficial prophylactic and therapeutic clinical effects, with a delay in disease onset and symptom severity.
相关产品：fda-approved drug library plus | drug repurposing compound library | fda-approved drug library mini | covalent screening library | fda-approved drug library | drug repurposing compound library plus | bioactive compound library plus | sbe-β-cd | cyclosporin a | h2dcfda | gw4869 | mptp hydrochloride | etomoxir | mitoquinone mesylate | bapta-am | gsk2795039 | jc-1 | monocrotaline | auranofin | d-luciferin | dapi dihydrochloride | dtt | cfse | solutol hs-15 | auxinole | bptes | ademetionine | nile red | nadph tetrasodium salt | mtt | isa-2011b | l-ascorbic acid | 3x flag peptide | propidium iodide | wnk463 | tocofersolan
MedChemExpress LLC
郑先生
86-021-58955995
17321200539
公明回收晨星芯片不限数量
济源静音发电机租赁租赁中心欢迎您 忠祥机械
消防排烟送风口 远程多叶排烟口
保温无缝钢管生产厂家
在步行街做安吉尔净水器好不好？
特立氟胺 Teriflunomide
周边磨床
武夷山泄水管厂家//泄水管出厂价
休闲零食人人爱吃,加盟澳脯道香开店有市场
辽宁改向滚筒制造厂家质优价廉就在本厂
央视上榜品牌地老板美缝剂十大品牌美缝剂招代理厂家招商
折叠式索伯网用于河流底栖动物定量采集适用于浅水操作。
供应安全防护雨衣 交通执法雨衣
仔猪断脐的细节以及常见误区
南山电极台车外壳供货商品质优良服务好
台湾牛樟芝抗老緊緻修護面膜 批发找许银鹭
全自动闭口闪点测定仪（新标准） FDT-0232
江米条油炸锅厂家 自动控制高低温
三面螺纹产品的模具设计怎么抽芯？
东风菱智 M5 2012款 2.0L 手动 7座 Q3长轴标准型